Paper microfluidics goes digital.

Fobel, Ryan; Kirby, Andrea E; Ng, Alphonsus H C; Farnood, Ramin R; Wheeler, Aaron R · Adv Mater · 2014

basic_science · Level V

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Abstract

The first example of so-called "digital microfluidics" (DMF) implemented on paper by inkjet printing is reported. A sandwich enzyme-linked immunosorbent assay (ELISA) is demonstrated as an example of a complex, multistep protocol that would be difficult to achieve with capillary-driven paper microfluidics. Furthermore, it is shown that paper-based DMF devices have comparable performance to traditional photolithographically patterned DMF devices at a fraction of the cost.

Medical subject headings