Volumetric breast density estimation from full-field digital mammograms: a validation study.
Where this comes from
- Record sourced from PubMed, PMID 24465808.
- Also identified by DOI 10.1371/journal.pone.0085952 and PMC identifier 3897574.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
OBJECTIVES: To objectively evaluate automatic volumetric breast density assessment in Full-Field Digital Mammograms (FFDM) using measurements obtained from breast Magnetic Resonance Imaging (MRI). MATERIAL AND METHODS: A commercially available method for volumetric breast density estimation on FFDM is evaluated by comparing volume estimates obtained from 186 FFDM exams including mediolateral oblique (MLO) and cranial-caudal (CC) views to objective reference standard measurements obtained from MRI. RESULTS: Volumetric measurements obtained from FFDM show high correlation with MRI data. Pearson's correlation coefficients of 0.93, 0.97 and 0.85 were obtained for volumetric breast density, breast volume and fibroglandular tissue volume, respectively. CONCLUSIONS: Accurate volumetric breast density assessment is feasible in Full-Field Digital Mammograms and has potential to be used in objective breast cancer risk models and personalized screening.
Medical subject headings
- Breast
- Mammography
- Radiographic Image Enhancement