Health-related quality of life in small-cell lung cancer: a systematic review on reporting of methods and clinical issues in randomised controlled trials.

Zikos, Efstathios; Ghislain, Irina; Coens, Corneel; Ediebah, Divine E; Sloan, Elizabeth; Quinten, Chantal; Koller, Michael; van Meerbeeck, Jan P et al. · Lancet Oncol · 2014

systematic_review · Level I

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Abstract

Small-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials.

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