Sex-specific aging in flies, worms, and missing great-granddads.

Finch, Caleb E; Tower, John · Cell · 2014

basic_science · Level V

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Abstract

Two recent studies identify how sex-specific pheromonal factors in flies and worms alter lifespan through metabolic pathways that are shared with mammals. Sex differences in human lifespans imply nonautonomous effects modulated by sex-specific gene-environment interactions that could still include pheromonal mechanisms.

Medical subject headings