Establishing a diagnostic road map for MUTYH-associated polyposis.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 24486588.
- Also identified by DOI 10.1158/1078-0432.CCR-13-3295 and PMC identifier 3996649.
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Abstract
The analysis of MUTYH-associated polyposis cases of the EPIPOLIP cohort confirms the importance of including serrated polyps in the diagnostic work-up of patients with oligopolyposis, suggests a role for screening polyps for the somatic c.34G>T KRAS mutation, and allows the implementation of a genetic testing strategy based on population data.
Medical subject headings
- Adenomatous Polyposis Coli
- Colonic Polyps
- Colorectal Neoplasms
- DNA Glycosylases
- Mutation