Thermally switchable polymers achieve controlled Escherichia coli detachment.

Hook, Andrew L; Chang, Chien-Yi; Scurr, David J; Langer, Robert; Anderson, Daniel G; Williams, Paul; Davies, Martyn C; Alexander, Morgan R · Adv Healthc Mater · 2014

basic_science · Level V

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Abstract

The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone; rather, the surface composition of the polymer plays the key role.

Medical subject headings