Genetic adaptation to diet preserves longevity.

Walhout, Albertha J M · Cell Metab · 2014

other · Level V

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Abstract

Diet affects cellular metabolism and organismal life history traits. Pang and Curran (2014) use Caenorhabditis elegans and its bacterial diets to unveil genetic perturbations in proline catabolism that shorten lifespan, but, only on specific Escherichia coli diets, thereby unveiling a genome-encoded adaptive response to different nutritional states.

Medical subject headings