Current progress of aptamer-based molecular imaging.
review · Level V
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- Record sourced from PubMed, PMID 24525205.
- Also identified by DOI 10.2967/jnumed.113.126144 and PMC identifier 4110511.
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Abstract
Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligand. Since their discovery, aptamers have been rapidly translated into clinical practice. They have been approved as therapeutics and molecular diagnostics. Aptamers also possess several properties that make them uniquely suited to molecular imaging. This review aims to provide an overview of aptamers' advantages as targeting ligands and their application in molecular imaging.
Medical subject headings
- Aptamers, Nucleotide
- Molecular Imaging