The 3DGD: a database of genome 3D structure.
basic_science · Level V
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- Record sourced from PubMed, PMID 24526713.
- Also identified by DOI 10.1093/bioinformatics/btu081.
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Abstract
The studies of chromatin 3D structure help us to understand its formation and function. Techniques combining chromosome conformation capture and next generation sequencing can capture chromatin structure information and has been applied to several different species and cell lines. We built 3DGD (3D Genome Database), a database that currently collected Hi-C data on four species, for easy accessing and visualization of chromatin 3D structure data. With the integration of other omics data such as genome-wide protein-DNA-binding data, this data source would be useful for researchers interested in chromatin structure and its biological functions. The 3DGD v1.1, data browser, downloadable files and documentation are available at: http://3dgd.biosino.org/.
Medical subject headings
- Chromatin
- Databases, Genetic
- Genome