Central neurogenic hyperventilation and renal tubular acidosis in children with pontine gliomas.

Ledet, Davonna; Delos Santos, Noel M; Khan, Raja; Gajjar, Amar; Broniscer, Alberto · Neurology · 2014

case_series · Level IV

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Abstract

Central neurogenic hyperventilation (CNH) is a rare neurologic condition that develops secondary to brainstem involvement. Approximately 35 noncomatose patients with CNH have been reported, including 7 with either a diffuse (patients 2–10 in the table) or focal (patient 1 in the table) brainstem glioma.<sup>1–7</sup> Although diffuse intrinsic pontine glioma (DIPG) is the most common pediatric brainstem cancer, only 1 case report described a child with DIPG who experienced CNH.<sup>6</sup>

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