Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24550068.
- Also identified by DOI 10.1002/adma.201304995 and PMC identifier 4146397.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.
Medical subject headings
- Acrylic Resins
- Biomimetic Materials
- Cell Differentiation
- Mesenchymal Stem Cells
- Temperature
- Tissue Scaffolds