Supramolecular nanofibrils inhibit cancer progression in vitro and in vivo.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24574174.
- Also identified by DOI 10.1002/adhm.201300645 and PMC identifier 4134730.
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Abstract
Self-assembly of small peptide derivatives affords supramolecular nanofibrils that possess characteristic features of amyloid oligomers. Acting as de novo amyloid oligomers, the nanofibrils effectively inhibit the tumor progression both in vitro and in vivo, which demonstrates a new type of anticancer approach and may provide new insights for inverse comorbidity between cancer and neurodegenerative diseases.
Medical subject headings
- Nanofibers
- Peptides