Photoactive electrospun fibers for inducing cell death.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24574265.
- Also identified by DOI 10.1002/adhm.201300318.
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Abstract
A photoactive electrospun material producing reactive oxygen species (ROS) upon light irradiation is reported. The phototoxicity of the generated ROS is spatially restricted to the fiber-tissue interface by conjugation of the photosensitizer to a macromolecule. Photo-triggered ROS is produced on demand and repeatedly. It induces death of mammalian cells growing on the material surface with high spatial resolution.
Medical subject headings
- Cell Death
- Electrochemical Techniques