Electrochemical control of the enzymatic polymerization of PEG hydrogels: formation of spatially controlled biological microenvironments.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24574303.
- Also identified by DOI 10.1002/adhm.201300479.
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Abstract
Control of pH gradient profile at the electrode-electrolyte interfaces allows the control of the enzymatic PEG-hydrogel polymerization. By tuning the solution pH, buffer capacity, and the applied current, the extent of the local inhibition and confinement of the Factor XIII-mediated polymerization of PEG are controlled. This technology opens new perspectives for the production of 3D-structured biological microenvironments.
Medical subject headings
- Biocompatible Materials
- Cell Engineering
- Electrochemical Techniques
- Hydrogel, Polyethylene Glycol Dimethacrylate
- Polyethylene Glycols