Interphase chromatin LINEd with RNA.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24581484.
- Also identified by DOI 10.1016/j.cell.2014.02.005.
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Abstract
RNA has been proposed to be a component of an underlying nuclear matrix. Hall et al. show that noncoding, repetitive RNAs, some derived from LINE1 elements, stably associate with interphase chromosomes and copurify with nuclear scaffold, indicating that RNAs might impact interphase chromosome architecture.
Medical subject headings
- Chromosomes, Mammalian
- Euchromatin
- Interphase
- RNA, Untranslated