Long-lasting HHV-6 reactivation in long-term adult survivors after double umbilical cord blood allogeneic stem cell transplantation.

Illiaquer, Marina; Malard, Florent; Guillaume, Thierry; Imbert-Marcille, Berthe-Marie; Delaunay, Jacques; Le Bourgeois, Amandine; Rimbert, Marie; Bressollette-Bodin, Celine et al. · J Infect Dis · 2014

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Abstract

Higher incidence of human herpesvirus 6 (HHV-6) infection has been documented after umbilical cord blood allo-transplant in adults. Here we demonstrate that HHV-6 reactivation persists for a very long time in half of the patients after this type of graft. Long-term immune reconstitution does not explain this event, which remains to be explained.

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