Microfluidic-assisted self-assembly of complex dendritic polyethylene drug delivery nanocapsules.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24610685.
- Also identified by DOI 10.1002/adma.201305753.
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Abstract
Microfluidic platform for the synthesis of complex nanocapsules is presented via a controlled self-assembly. The monodisperse nanocapsules in the range of 50-200 nm consist of a dendritic polyethylene core and a Pluronic copolymer shell. The resultant nanocarriers encapsulate large amount of hydrophobic anticancer drug like paclitaxel while providing a low complement activation as well as sustained release profile with high tunability.
Medical subject headings
- Dendrimers
- Microfluidic Analytical Techniques
- Nanocapsules
- Polyethylene