Microfluidic-based generation of size-controlled, biofunctionalized synthetic polymer microgels for cell encapsulation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24615922.
- Also identified by DOI 10.1002/adma.201304880 and PMC identifier 4058833.
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Abstract
Cell and islet microencapsulation in synthetic hydrogels provides an immunoprotective and cell-supportive microenvironment. A microfluidic strategy for the genaration of biofunctionalized, synthetic microgel particles with precise control over particle size and molecular permeability for cell and protein delivery is presented. These engineered capsules support high cell viability and function of encapsulated human stem cells and islets.
Medical subject headings
- Hydrogels
- Islets of Langerhans
- Mesenchymal Stem Cells
- Microfluidic Analytical Techniques
- Polymers