Spatial mapping and quantification of soft and hard protein coronas at silver nanocubes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24617413.
- Also identified by DOI 10.1021/nl500277c.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Protein coronas around silver nanocubes were quantified in serum-containing media using localized surface plasmon resonances. Both soft and hard coronas showed exposure-time and concentration-dependent changes in protein surface density with time-dependent hardening. We observed spatially dependent kinetics of the corona-formation at cube edges/corners versus facets at short incubation times, where the polymer stabilization agent delayed corona hardening. The soft corona contained more protein than the hard corona at all time-points (8-fold difference with 10% serum conditions).
Medical subject headings
- Blood Proteins
- Metal Nanoparticles
- Silver
- Surface Plasmon Resonance