Maladapted endothelial cells flip the mesenchymal switch.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24622512.
- Also identified by DOI 10.1126/scitranslmed.3008623.
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Abstract
Endothelial cells in the neointima undergo a transition to the mesenchymal phenotype, suggesting a therapeutic target for vein graft restenosis (Cooley et al., this issue).
Medical subject headings
- Cell Transdifferentiation
- Endothelial Cells
- Mesoderm
- Signal Transduction
- Transforming Growth Factor beta
- Veins