Circuits controlling energy balance and mood: inherently intertwined or just complicated intersections?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24630814.
- Also identified by DOI 10.1016/j.cmet.2014.02.008 and PMC identifier 4047152.
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Abstract
Recent reports of adverse psychiatric events from seemingly different types of weight loss therapies highlight a previously underestimated overlap between CNS circuits that control energy balance and those that regulate mood. In this Perspective, we discuss a few potential brain sites where the homeostatic and the hedonic pathways may intersect and suggest that a better understanding of both pathways is necessary for the development of more effective and safer antiobesity therapies.
Medical subject headings
- Affect
- Appetite Depressants
- Energy Metabolism
- Mood Disorders
- Obesity