Integrating oxaliplatin with highly luminescent carbon dots: an unprecedented theranostic agent for personalized medicine.

Zheng, Min; Liu, Shi; Li, Jing; Qu, Dan; Zhao, Haifeng; Guan, Xingang; Hu, Xiuli; Xie, Zhigang et al. · Adv Mater · 2014

basic_science · Level V

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Abstract

A theranostic nanomedicine (CD-Oxa) is synthesized by means of the condensation reaction between the amino groups on the surface of fluorescent carbon dots (CDs) and the carboxyl group of the oxaliplatin derivative Oxa(IV)-COOH. CD-Oxa, which integrates the optical properties of CDs and the anticancer function of oxaliplatin, could be used for simultaneous drug delivery and fluorescent tracking.

Medical subject headings