Nanoparticles for imaging, sensing, and therapeutic intervention.
review · Level V
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- Record sourced from PubMed, PMID 24641589.
- Also identified by DOI 10.1021/nn500962q and PMC identifier 4123720.
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Abstract
Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.
Medical subject headings
- Biocompatible Materials
- Molecular Imaging
- Nanomedicine
- Nanoparticles