A universal approach to crosslinked hierarchical polymer multilayers as stable and highly effective antifouling coatings.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24652687.
- Also identified by DOI 10.1002/adma.201304737.
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Abstract
Material-independent and bioinert hierarchical polymer multilayer coatings are presented. Chemically active catecholic hyperbranched polyglycerols (hPGs) form a foundation layer on a versatile surface via multivalent anchoring and crosslinking, the activity of which is shielded by the bioinert catecholic hPGs. Mono-catecholic hPGs finally terminate all of the free catechols to build a flexible bioinert top layer. These coatings perfectly prevent protein and cell adhesion.
Medical subject headings
- Catechols
- Cell Adhesion
- Coated Materials, Biocompatible
- Equipment Contamination
- Glycerol
- Polymers
- Proteins