Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy.

Ahn, Sukyung; Lee, In-Hyun; Kang, Sukmo; Kim, Daejin; Choi, Minsuk; Saw, Phei Er; Shin, Eui-Cheol; Jon, Sangyong · Adv Healthc Mater · 2014

basic_science · Level V

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Abstract

Golden vaccine for cancers. Gold nanoparticles enable efficient antigen delivery to dendritic cells and then activate the cells to facilitate cross-presentation, inducing antigen-specific cytotoxic T-lymphocyte responses for effective cancer therapy.

Medical subject headings