Minimal residual disease in breast cancer: in blood veritas.

Siravegna, Giulia; Bardelli, Alberto · Clin Cancer Res · 2014

editorial · Level V

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Abstract

A blood-based molecular test might direct recommendations for systemic therapies in patients with early-stage breast cancer undergoing surgery with curative intent. A new study suggests that droplet digital PCR (ddPCR) can be used to detect cancer-specific DNA alterations in plasma with sensitivity suitable for monitoring minimal residual disease.

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