Differentiation between calcification and hemorrhage in brain tumors using susceptibility-weighted imaging: a pilot study.

Berberat, Jatta; Grobholz, Rainer; Boxheimer, Larissa; Rogers, Susanne; Remonda, Luca; Roelcke, Ulrich · AJR Am J Roentgenol · 2014

case_series · Level IV

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Abstract

Our aim was to develop a robust method to differentiate calcification from hemorrhage in gliomas. Histopathologic examination was performed to validate hemorrhage and calcification. Phase images from eleven patients with glioma yielded statistically significant phase-shift values for calcification and hemorrhage compared with normal brain, whereas CT showed substantial overlap of Hounsfield units. Phase image analysis correctly differentiated between intratumoral calcification and hemorrhage in 86% of cases.

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