A case of rabies encephalitis: new dog, old tricks.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 24663232.
- Also identified by DOI 10.1212/WNL.0000000000000249 and PMC identifier 3962988.
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Abstract
A 41-year-old Canadian man presented with a 1-week history of new bizarre behavior including agoraphobia. Nested PCR confirmed the presence of rabies in both nuchal snips and saliva. An initial MRI with gadolinium enhancement was normal. On day 8, repeat neuroimaging revealed new cranial nerve enhancement and slight hyperintensities of the caudate nuclei bilaterally (figure). This is consistent with cranial nerve involvement reported in animal studies<sup>1</sup> and with a remote report of electron microscopic evidence of rabies virus in trigeminal ganglion cells reported in 2 human cases.<sup>2</sup>
Medical subject headings
- Encephalitis
- Rabies
- Rabies virus