The role of surface functionality in nanoparticle exocytosis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24665047.
- Also identified by DOI 10.1002/adhm.201400001 and PMC identifier 4134693.
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Abstract
Getting out is just as important for nano-therapeutics as getting in. Exocytosis rates determine residency time in the cell, an important determinant for therapeutic efficacy and also for eventual clearance from the cell. In this study, it is shown that exocytosis efficiency is determined by surface functionality, providing a strategy for optimizing nanocarriers.
Medical subject headings
- Drug Carriers
- Nanoparticles