"The race" to clone BRCA1.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 24675952.
- Also identified by DOI 10.1126/science.1251900.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The existence of BRCA1 was proven in 1990 by mapping predisposition to young-onset breast cancer in families to chromosome 17q21. Knowing that such a gene existed and approximately where it lay triggered efforts by public and private groups to clone and sequence it. The press baptized the competition "the race" and reported on it in detail for the next 4 years. BRCA1 was positionally cloned in September 1994. Twenty years later, I reflect on "the race" and its consequences for breast cancer prevention and treatment.
Medical subject headings
- BRCA1 Protein
- Breast Neoplasms
- Chromosomes, Human, Pair 17