Drug delivery with PEGylated MoS2 nano-sheets for combined photothermal and chemotherapy of cancer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24677423.
- Also identified by DOI 10.1002/adma.201305256.
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Abstract
MoS2 nanosheets functionalized with poly-ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near-infrared absorbance of MoS2, combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti-tumor effect upon systemic administration.
Medical subject headings
- Antineoplastic Agents
- Disulfides
- Drug Carriers
- Molybdenum
- Nanostructures
- Phototherapy
- Polyethylene Glycols