Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 24699072.
- Also identified by DOI 10.1371/journal.pone.0089639 and PMC identifier 3974663.
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Abstract
Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI.
Medical subject headings
- Anti-HIV Agents
- Drug Resistance, Viral
- HIV Infections
- HIV-1
- Viral Load