Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.
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- Record sourced from PubMed, PMID 24699454.
- Also identified by DOI 10.1371/journal.pone.0093942 and PMC identifier 3974843.
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Abstract
The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.
Medical subject headings
- Dihydropteroate Synthase
- Drug Resistance
- Plasmodium malariae
- Polymorphism, Genetic