9-1-1: HSCs respond to emergency calls.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24702988.
- Also identified by DOI 10.1016/j.stem.2014.03.010 and PMC identifier 4042390.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In this issue of Cell Stem Cell, Zhao et al. (2014) and Schürch et al. (2014) describe two new stem cell mechanisms underlying protective responses to infection. In response to inflammatory signals, HSPCs and MSCs produce cytokines that stimulate HSC mobilization and differentiation toward innate immune cells at the expense of adaptive immune lineages.
Medical subject headings
- CD8-Positive T-Lymphocytes
- Cell Differentiation
- Cytokines
- Hematopoiesis
- Hematopoietic Stem Cells
- Mesenchymal Stem Cells
- Multipotent Stem Cells
- Myeloid Cells
- Myelopoiesis
- Stress, Physiological
- T-Lymphocytes, Cytotoxic