Acetyl-CoA synthetase is a conserved regulator of autophagy and life span.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 24703691.
- Also identified by DOI 10.1016/j.cmet.2014.03.021 and PMC identifier 4036695.
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Abstract
Autophagy is essential for the maintenance of cellular homeostasis during periods of stress. Eisenberg and colleagues (Eisenberg et al., 2014) now describe the central and conserved role for acetyl-CoA synthetase in regulating life span in yeast and flies by a mechanism involving autophagy.
Medical subject headings
- Autophagy
- Coenzyme A Ligases
- Drosophila Proteins
- Longevity