Photo-patterning of non-fouling polymers and biomolecules on paper.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24719300.
- Also identified by DOI 10.1002/adma.201401006.
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Abstract
Functional cellulose substrates with tetrazole moieties are generated to serve as universal platforms for the spatio-temporal immobilization of synthetic ultra-low fouling polymer brushes and protein species via a nitrile imine-mediated tetrazole-ene cycloaddition (NITEC)-based protocol. Poly(carboxybetaine acrylamide) brushes are grafted from initiators photo-patterned by NITEC utilizing single electron transfer living radical polymerization. Streptavidin is photo-immobilized with remarkable efficiency, opening the possibility to generate new materials for biomedical and biosensing applications.
Medical subject headings
- Biosensing Techniques
- Immunoassay
- Molecular Imprinting
- Paper
- Photography
- Protein Array Analysis
- Streptavidin