Multiplying messages LRRK beneath Parkinson disease.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24725399.
- Also identified by DOI 10.1016/j.cell.2014.03.043.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Parkinson Disease (PD) is a progressive neurodegenerative disorder with limited therapeutic options. In this issue of Cell, Martin et al. link PD protein leucine-rich repeat kinase 2 (LRRK2) to abnormalities of translational control, a pathogenic mechanism implicated in an increasing number of CNS neurodegenerative diseases, as well as in normal aging.
Medical subject headings
- Neurons
- Parkinson Disease
- Protein Serine-Threonine Kinases
- Ribosomal Proteins