A novel poly(amido amine)-dendrimer-based hydrogel as a mimic for the extracellular matrix.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24729192.
- Also identified by DOI 10.1002/adma.201400323.
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Abstract
The extracellular matrix is mimicked by a novel dendrimer-based hydrogel, which exhibits a highly interconnected porous network, enhanced mechanical stiffness, and a low swelling ratio. The hydrogel system supports the proliferation and differentiation of mesenchymal stem cells without any cytotoxic effects. This dendrimer-based hydrogel may serve as a model for developing new advanced materials with applications in tissue engineering.
Medical subject headings
- Biomimetic Materials
- Dendrimers
- Extracellular Matrix
- Mesenchymal Stem Cells
- Polyesters
- Polyethylene Glycols
- Tissue Engineering