The cell-engineered construct of cartilage on the basis of biopolymer hydrogel matrix and human adipose tissue-derived mesenchymal stromal cells (in vitro study).
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24737713.
- Also identified by DOI 10.1002/jbm.a.35197.
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Abstract
The study results of in vitro formation of tissue-engineered cartilage construct on the basis of cell-engineered construct composed of biopolymer hydrogel matrix and human adipose tissue-derived mesenchymal stromal cells (hADSCs) are presented. It was revealed that hADSCs in biopolymer hydrogel matrix Sphero®GEL under chondrogenic conditions generate three-dimensional structures and produce cartilaginous extracellular matrix components: collagen type II and glycosaminoglycans.
Medical subject headings
- Adipose Tissue
- Cartilage
- Cell Differentiation
- Cell Engineering
- Chondrogenesis
- Hydrogels
- Mesenchymal Stem Cells