Emergence of Zaire Ebola virus disease in Guinea.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 24738640.
- Also identified by DOI 10.1056/NEJMoa1404505.
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Abstract
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.
Medical subject headings
- Disease Outbreaks
- Ebolavirus
- Hemorrhagic Fever, Ebola