Hydrocephalus in neuromyelitis optica.

Clardy, Stacey L; Lucchinetti, Claudia F; Krecke, Karl N; Lennon, Vanda A; O'Toole, Orna; Weinshenker, Brian G; Boyd, Clara D; Krieger, Stephen et al. · Neurology · 2014

case_series · Level IV

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Abstract

A majority of patients with neuromyelitis optica (NMO) spectrum disorders (NMOSD) have MRI brain abnormalities, some of which are “NMO-typical” with localization in aquaporin 4 (AQP4)–rich circumventricular and periaqueductal regions.<sup>1</sup> Although uncommon in adult patients, symptomatic brain involvement occurs in approximately 50% of NMO–immunoglobulin G (IgG) seropositive children. Here we report the clinical characteristics, type, and frequency of hydrocephalus in NMOSD.

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