Land-applied goat manure as a source of human Q-fever in the Netherlands, 2006-2010.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 24788538.
- Also identified by DOI 10.1371/journal.pone.0096607 and PMC identifier 4008588.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Studies have shown a link between Q-fever positive farms (QFPFs) and community cases of human Q-fever. Our study is the first to investigate the potential role of contaminated land-applied manure in human Q-fever, based on a large set of nationwide notification and farm management data. Time between manure application and disease onset in geographically linked notified human cases coincided with the incubation period of Q-fever. Proximity of contaminated land parcels predicted human cases better than proximity of QFPFs (80% vs. 58%, 0-5 km in 2009). Incidence around QFPFs and contaminated land parcels decreased with distance, but not around non-contaminated land parcels. Incidence was higher around contaminated land parcels than non-contaminated land parcels (RR = [10],95%CI = [7], [1]-[14,2]). Our findings deliver evidence that, apart from QFPFs, land-applied contaminated manure may be another source of human Q-fever.
Medical subject headings
- Coxiella burnetii
- Goat Diseases
- Manure
- Q Fever
- Zoonoses