Brain communication in a completely locked-in patient using bedside near-infrared spectroscopy.
case_report · Level V
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- Record sourced from PubMed, PMID 24789862.
- Also identified by DOI 10.1212/WNL.0000000000000449 and PMC identifier 4049706.
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Abstract
Amyotrophic lateral sclerosis (ALS) can result in the locked-in state (LIS), characterized by paralysis, and eventual respiratory failure, compensated by artificial ventilation,<sup>1</sup> or the completely LIS (CLIS), with additional total paralysis of eye muscles. Brain–computer interfaces (BCIs) have been used to allow paralyzed people to regain basic communication,<sup>2</sup> although current EEG-based BCIs have not succeeded with CLIS patients.<sup>3</sup> We present Class IV case evidence to establish that communication in the CLIS is possible with a metabolic BCI based on near-infrared spectroscopy (NIRS).
Medical subject headings
- Brain
- Brain-Computer Interfaces
- Communication
- Quadriplegia