Aging stem cells: transcriptome meets epigenome meets methylome.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24792109.
- Also identified by DOI 10.1016/j.stem.2014.04.013.
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Abstract
Aging is associated with impairments in hematopoietic stem cell (HSC) function and an increased risk of leukemogenesis. In this issue of Cell Stem Cell, Sun et al. (2014) use highly purified HSCs along with an integrated genomic approach to evaluate aging-associated alterations in the epigenome and transcriptome of HSCs.
Medical subject headings
- Epigenomics
- Hematopoietic Stem Cells