Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24792111.
- Also identified by DOI 10.1016/j.stem.2014.04.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.
Medical subject headings
- Cellular Reprogramming
- Hematopoietic Stem Cells
- Transcription Factors