Chemotherapy-induced hand-foot syndrome and nail changes: a review of clinical presentation, etiology, pathogenesis, and management.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24795111.
- Also identified by DOI 10.1016/j.jaad.2014.03.019.
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Abstract
Chemotherapy-induced hand-foot syndrome and nail changes are common complications of many classic chemotherapeutic agents and the newer molecular targeted therapies. They significantly impact patient quality of life, and frequently necessitate chemotherapy dose intensity modification or reduction. We aim to describe the epidemiology, pathogenesis, clinical presentation, and current evidence-based treatment options for these entities.
Medical subject headings
- Antineoplastic Agents
- Hand-Foot Syndrome
- Nail Diseases