Modeling the effect of different vaccine effectiveness estimates on the number of vaccine-prevented influenza-associated hospitalizations in older adults.

Fry, Alicia M; Kim, Inkyu K; Reed, Carrie; Thompson, Mark; Chaves, Sandra S; Finelli, Lyn; Bresee, Joseph · Clin Infect Dis · 2014

other · Level V

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Abstract

We compared influenza vaccine-prevented hospitalizations in adults aged ≥65 years for a range of hypothetical effectiveness estimates. During 2012-2013, a vaccine with 10% effectiveness (66% coverage) would have averted approximately 13 000 hospitalizations, and a vaccine with 40% effectiveness would have averted approximately 60 000 hospitalizations. Annual vaccination is merited in this vulnerable population.

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