Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network.

Simari, Robert D; Pepine, Carl J; Traverse, Jay H; Henry, Timothy D; Bolli, Roberto; Spoon, Daniel B; Yeh, Ed; Hare, Joshua M et al. · Circ Res · 2014

review · Level V

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Abstract

To understand the role of bone marrow mononuclear cells in the treatment of acute myocardial infarction, this overview offers a retrospective examination of strengths and limitations of 3 contemporaneous trials with attention to critical design features and provides an analysis of the combined data set and implications for future directions in cell therapy for acute myocardial infarction.

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