Testis cancer: the forgotten poster child.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 24812412.
- Also identified by DOI 10.1158/1078-0432.CCR-14-0691.
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Abstract
In germ cell cancers, the unique reversibility of malignancy and the balance between somatic differentiation and dedifferentiation may be critical to late relapse that is dominated by non-germ cell elements. Targeting regulators of differentiation may provide a solution, and this may be elucidated via serial liquid biopsies (via circulating tumor cells).
Medical subject headings
- Neoplasms, Germ Cell and Embryonal
- Testicular Neoplasms