SnapShot: Epithelial tight junctions.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24813618.
- Also identified by DOI 10.1016/j.cell.2014.04.027.
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Abstract
Tight junctions form a morphological and functional border between the apical and basolateral cell surface domains that serves as a paracellular diffusion barrier, enabling epithelial cells to separate compartments of different composition. Tight junctions also contribute to the generation and maintenance of cell polarity and regulate signaling mechanisms that guide cell behavior, shape, and gene expression. This SnapShot illustrates their components, organization, and functions.
Medical subject headings
- Epithelial Cells
- Tight Junctions